Fire crews from Warsop, Worksop and Mansfield Fire Station as well as Clowne Fire Station are also in attendance.
Ch Insp Neil Humphris said: "This is a major incident and emergency services will remain at the scene throughout the night.
"Multiple properties have been evacuated as we work with our partners to respond to this incident and understand how it happened."
The Crown Place Community Centre was opened for residents and police remained at the scene to provide assistance.
Karolina Ciolko, who lives nearby, told the BBC: "I was lying in bed when I heard an explosion.
"I quickly looked out the window. I saw smoke and the car in front of me rocked and the alarm went off. We quickly ran out of the house to see what had happened."
Karolina CiolkoMultiples homes have been evacuated
